Adrenal Cancer

Adrenal cancer, also known as adrenal cortical carcinoma, is a rare type of cancer that develops in the adrenal glands. The adrenal glands are small, triangular-shaped glands located on top of each kidney. They produce hormones that are essential for regulating various bodily functions, including metabolism, blood pressure, and response to stress.

Adrenal cancer typically begins in the outer layer of the adrenal glands, called the adrenal cortex, which produces hormones such as cortisol, aldosterone, and androgens. The exact cause of adrenal cancer is often unknown, but certain factors may increase the risk, including genetic conditions such as Li-Fraumeni syndrome and Beckwith-Wiedemann syndrome, as well as a history of radiation therapy to the abdomen.

Symptoms of adrenal cancer may vary depending on the hormones produced by the tumor. Common signs and symptoms may include:

• Abdominal pain or discomfort.

• Unintended weight loss.

• Changes in hormone levels, leading to symptoms such as high blood pressure, excessive hair growth, or irregular menstrual periods.

• A palpable mass or lump in the abdomen.

• Fatigue or weakness.

• Fever.